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First train05:12
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Last train23:22
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Avg changes2
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Fastest journey10hr 58m
Travelling from Prague to Brussels by train
The fastest trains from Prague to Brussels take around 10 hours and 58 minutes, covering a distance of approximately 721 kilometres. There are frequent services on the rail route between Prague and Brussels.
Journeys between Prague and Brussels usually involve 2 changes of train.
We usually find around 17 departures on the route from Prague to Brussels every weekday that leave enough time to change trains without waiting around for longer than necessary.
Trains are typically more frequent on weekends, when we found around 18 departures. The duration is normally about 10 hours and 58 minutes, whatever time you make the journey.
On weekdays the earliest train to Brussels is usually scheduled to depart Prague around 05:12 and the last train is around 23:22. This is the same at the weekend.
Route map is indicative only and may differ from the optimal route. Actual routes will be displayed when searching.
When to book Prague to Brussels train tickets?
The earlier you book the better, and the cheapest tickets we've found for trains from Prague to Brussels are £36.50.
Trains departing 30 days in advance will cost around £46 while booking 7 days in advance the price is around £73. Booking on the day of travel is likely to be more expensive, so it is worth booking in advance if you can to save money.
Trains for this journey usually open for booking around 6 months in advance. If booking is not yet open for your dates then you can set a booking alert to receive an email on the day that the cheapest tickets are released for your journey from Prague to Brussels by train.
Which trains operate between Prague and Brussels?
More than one type of train operates on the route from Prague to Brussels, so you’ll be travelling with one or more of the following rail operators:
- Eurocity (EC)
- Express-Zug
- ICE
- Intercity
- Intercity-Express (ICE)
- Intercités
- Mitteldeutsche Regiobahn
- Regionalbahn
- S-Bahn
- Thalys
You can check which train you’ll be travelling on by looking for the train name in search results.
Route map is indicative only and may differ from the optimal route. Actual routes will be displayed when searching.
Other journeys to Brussels View all journeys to Brussels
- From London from £44.00
- From Amsterdam from £26.50
- From Birmingham from £173.50
- From Edinburgh from £70.50
- From Cologne from £17.50
- From Rotterdam from £26.50
- From Paris from £26.50
- From Frankfurt am Main from £36.00
- From Munich from £36.50
- From Hamburg from £36.50
- From Vienna from £45.00
- From Stuttgart from £36.00
- From Salzburg from £36.00
- From Düsseldorf from £18.00
- From Copenhagen from £44.50
- From Lille from £17.50
- From Basel from £36.00
- From Zurich from £36.00
- From Lyon from £58.50
- From Antwerp from £7.50
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